RNA Details
Disease Name
diabetic cardiomyopathy
Tissue
heart
RNA Symbol
mir-18a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
PCR; immunofluorescence etc.
Target
NOTCH2
Pathway
NOTCH SIGNALING PATHWAY
PubMed ID
Title
MiR-18a-5p inhibits endothelial-mesenchymal transition and cardiac fibrosis through the Notch2 pathway
Year
2017
Function
The overexpression of miR-18a-5p could downregulate NOTCH3 expression and subsequently suppress endothelial-to-mesenchymal transition (EndMT).